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Homology and enzymatic requirements of microhomology-dependent alternative end joining
Nonhomologous DNA end joining (NHEJ) is one of the major double-strand break (DSB) repair pathways in higher eukaryotes. Recently, it has been shown that alternative NHEJ (A-NHEJ) occurs in the absence of classical NHEJ and is implicated in chromosomal translocations leading to cancer. In the presen...
Autores principales: | Sharma, S, Javadekar, S M, Pandey, M, Srivastava, M, Kumari, R, Raghavan, S C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385936/ https://www.ncbi.nlm.nih.gov/pubmed/25789972 http://dx.doi.org/10.1038/cddis.2015.58 |
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