Cargando…

Life or death by NFκB, Losartan promotes survival in dy(2J)/dy(2J) mouse of MDC1A

Inflammation and fibrosis are well-defined mechanisms involved in the pathogenesis of the incurable Laminin α2-deficient congenital muscular dystrophy (MDC1A), while apoptosis mechanism is barely discussed. Our previous study showed treatment with Losartan, an angiotensin II type I receptor antagoni...

Descripción completa

Detalles Bibliográficos
Autores principales: Elbaz, M, Yanay, N, Laban, S, Rabie, M, Mitrani-Rosenbaum, S, Nevo, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385938/
https://www.ncbi.nlm.nih.gov/pubmed/25766329
http://dx.doi.org/10.1038/cddis.2015.60