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Life or death by NFκB, Losartan promotes survival in dy(2J)/dy(2J) mouse of MDC1A
Inflammation and fibrosis are well-defined mechanisms involved in the pathogenesis of the incurable Laminin α2-deficient congenital muscular dystrophy (MDC1A), while apoptosis mechanism is barely discussed. Our previous study showed treatment with Losartan, an angiotensin II type I receptor antagoni...
Autores principales: | Elbaz, M, Yanay, N, Laban, S, Rabie, M, Mitrani-Rosenbaum, S, Nevo, Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385938/ https://www.ncbi.nlm.nih.gov/pubmed/25766329 http://dx.doi.org/10.1038/cddis.2015.60 |
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