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TRPC1-mediated Ca(2+) entry is essential for the regulation of hypoxia and nutrient depletion-dependent autophagy

Autophagy is a cellular catabolic process needed for the degradation and recycling of protein aggregates and damaged organelles. Although Ca(2+) is suggested to have an important role in cell survival, the ion channel(s) involved in autophagy have not been identified. Here we demonstrate that increa...

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Detalles Bibliográficos
Autores principales: Sukumaran, P, Sun, Y, Vyas, M, Singh, B B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385947/
https://www.ncbi.nlm.nih.gov/pubmed/25741599
http://dx.doi.org/10.1038/cddis.2015.7