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TRPC1-mediated Ca(2+) entry is essential for the regulation of hypoxia and nutrient depletion-dependent autophagy
Autophagy is a cellular catabolic process needed for the degradation and recycling of protein aggregates and damaged organelles. Although Ca(2+) is suggested to have an important role in cell survival, the ion channel(s) involved in autophagy have not been identified. Here we demonstrate that increa...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385947/ https://www.ncbi.nlm.nih.gov/pubmed/25741599 http://dx.doi.org/10.1038/cddis.2015.7 |