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The neutrophil–lymphocyte ratio and its utilisation for the management of cancer patients in early clinical trials

BACKGROUND: Inflammation is critical to the pathogenesis and progression of cancer, with a high neutrophil–lymphocyte ratio (NLR) associated with poor prognosis. The utility of studying NLR in early clinical trials is unknown. METHODS: This retrospective study evaluated 1300 patients treated in phas...

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Detalles Bibliográficos
Autores principales: Kumar, R, Geuna, E, Michalarea, V, Guardascione, M, Naumann, U, Lorente, D, Kaye, S B, de Bono, J S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385959/
https://www.ncbi.nlm.nih.gov/pubmed/25719834
http://dx.doi.org/10.1038/bjc.2015.67