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Hairy/enhancer-of-split related with YRPW motif protein 1 promotes osteosarcoma metastasis via matrix metallopeptidase 9 expression

BACKGROUND: Activation of the Notch pathway has been reported in various types of cancers. However, the role of the hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1) in osteosarcoma is unknown. We examined the function of HEY1 in osteosarcoma. METHODS: Expression of HEY1 was studied i...

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Detalles Bibliográficos
Autores principales: Tsuru, A, Setoguchi, T, Matsunoshita, Y, Nagao-Kitamoto, H, Nagano, S, Yokouchi, M, Maeda, S, Ishidou, Y, Yamamoto, T, Komiya, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385965/
https://www.ncbi.nlm.nih.gov/pubmed/25742474
http://dx.doi.org/10.1038/bjc.2015.84