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Pericytes contribute to airway remodeling in a mouse model of chronic allergic asthma

Myofibroblast accumulation, subepithelial fibrosis, and vascular remodeling are complicating features of chronic asthma, but the mechanisms are not clear. Platelet-derived growth factors (PDGFs) regulate the fate and function of various mesenchymal cells and have been implicated as mediators of lung...

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Detalles Bibliográficos
Autores principales: Johnson, Jill R., Folestad, Erika, Rowley, Jessica E., Noll, Elisa M., Walker, Simone A., Lloyd, Clare M., Rankin, Sara M., Pietras, Kristian, Eriksson, Ulf, Fuxe, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385988/
https://www.ncbi.nlm.nih.gov/pubmed/25637607
http://dx.doi.org/10.1152/ajplung.00286.2014