Absence of SARM1 Rescues Development and Survival of NMNAT2-Deficient Axons

SARM1 function and nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) loss both promote axon degeneration, but their relative relationship in the process is unknown. Here, we show that NMNAT2 loss and resultant changes to NMNAT metabolites occur in injured SARM1-deficient axons despite their...

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Detalles Bibliográficos
Autores principales: Gilley, Jonathan, Orsomando, Giuseppe, Nascimento-Ferreira, Isabel, Coleman, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386025/
https://www.ncbi.nlm.nih.gov/pubmed/25818290
http://dx.doi.org/10.1016/j.celrep.2015.02.060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386025/
https://www.ncbi.nlm.nih.gov/pubmed/25818290
http://dx.doi.org/10.1016/j.celrep.2015.02.060

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