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Absence of SARM1 Rescues Development and Survival of NMNAT2-Deficient Axons
SARM1 function and nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) loss both promote axon degeneration, but their relative relationship in the process is unknown. Here, we show that NMNAT2 loss and resultant changes to NMNAT metabolites occur in injured SARM1-deficient axons despite their...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386025/ https://www.ncbi.nlm.nih.gov/pubmed/25818290 http://dx.doi.org/10.1016/j.celrep.2015.02.060 |