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A small-fish model for behavioral-toxicological screening of new antimalarial drugs: a comparison between erythro- and threo-mefloquine

BACKGROUND: New antimalarial drugs need to be developed because over time resistance against the existing drugs develops. Furthermore, some of the drugs have severe side effects. Here we describe a behavioral small-fish model for early detection of neurotoxic effects of new drugs. As case example we...

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Detalles Bibliográficos
Autores principales: Maaswinkel, Hans, Zhu, Liqun, Weng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386100/
https://www.ncbi.nlm.nih.gov/pubmed/25886204
http://dx.doi.org/10.1186/s13104-015-1088-x