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GEM-loaded magnetic albumin nanospheres modified with cetuximab for simultaneous targeting, magnetic resonance imaging, and double-targeted thermochemotherapy of pancreatic cancer cells

BACKGROUND: Targeted delivery is a promising strategy to improve the diagnostic imaging and therapeutic effect of cancers. In this paper, novel cetuximab (C225)-conjugated, gemcitabine (GEM)-containing magnetic albumin nanospheres (C225-GEM/MANs) were fabricated and applied as a theranostic nanocarr...

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Detalles Bibliográficos
Autores principales: Wang, Ling, An, Yanli, Yuan, Chenyan, Zhang, Hao, Liang, Chen, Ding, Fengan, Gao, Qi, Zhang, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386779/
https://www.ncbi.nlm.nih.gov/pubmed/25848268
http://dx.doi.org/10.2147/IJN.S77642