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Prostanoid therapies in the management of pulmonary arterial hypertension

Prostacyclin is an endogenous eicosanoid produced by endothelial cells; through actions on vascular smooth-muscle cells, it promotes vasodilation. Pulmonary arterial hypertension (PAH) is characterized by elevated mean pulmonary artery pressure due to a high pulmonary vascular resistance state. A re...

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Detalles Bibliográficos
Autor principal: LeVarge, Barbara L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386780/
https://www.ncbi.nlm.nih.gov/pubmed/25848300
http://dx.doi.org/10.2147/TCRM.S75122