Poly(lactic-co-glycolic acid) nanoparticles conjugated with CD133 aptamers for targeted salinomycin delivery to CD133(+) osteosarcoma cancer stem cells

BACKGROUND: Cancer stem cells (CSCs) possess the characteristics associated with normal stem cells and are responsible for cancer initiation, recurrence, and metastasis. CD133 is regarded as a CSCs marker of osteosarcoma, which is the most common primary bone malignancy in childhood and adolescence....

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Ni, Miaozhong, Xiong, Min, Zhang, Xinchao, Cai, Guoping, Chen, Huaiwen, Zeng, Qingmin, Yu, Zuochong
Format: Online Artikel Text
Sprache:English
Veröffentlicht: Dove Medical Press 2015
Schlagworte:
Original Research
Online Zugang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386781/
https://www.ncbi.nlm.nih.gov/pubmed/25848270
http://dx.doi.org/10.2147/IJN.S78498

Online

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386781/
https://www.ncbi.nlm.nih.gov/pubmed/25848270
http://dx.doi.org/10.2147/IJN.S78498

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