Dose-Dependent Effects of Morphine Exposure on mRNA and microRNA (miR) Expression in Hippocampus of Stressed Neonatal Mice

Morphine is used to sedate critically ill infants to treat painful or stressful conditions associated with intensive care. Whether neonatal morphine exposure affects microRNA (miR) expression and thereby alters mRNA regulation is unknown. We tested the hypothesis that repeated morphine treatment in...

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Detalles Bibliográficos
Autores principales: McAdams, Ryan M., McPherson, Ronald J., Beyer, Richard P., Bammler, Theo K., Farin, Frederico M., Juul, Sandra E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386824/
https://www.ncbi.nlm.nih.gov/pubmed/25844808
http://dx.doi.org/10.1371/journal.pone.0123047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386824/
https://www.ncbi.nlm.nih.gov/pubmed/25844808
http://dx.doi.org/10.1371/journal.pone.0123047

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