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Dose-Dependent Effects of Morphine Exposure on mRNA and microRNA (miR) Expression in Hippocampus of Stressed Neonatal Mice
Morphine is used to sedate critically ill infants to treat painful or stressful conditions associated with intensive care. Whether neonatal morphine exposure affects microRNA (miR) expression and thereby alters mRNA regulation is unknown. We tested the hypothesis that repeated morphine treatment in...
Autores principales: | McAdams, Ryan M., McPherson, Ronald J., Beyer, Richard P., Bammler, Theo K., Farin, Frederico M., Juul, Sandra E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386824/ https://www.ncbi.nlm.nih.gov/pubmed/25844808 http://dx.doi.org/10.1371/journal.pone.0123047 |
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