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Role of the MPTP in conditioning the heart – translatability and mechanism

Mitochondria have long been known to be the gatekeepers of cell fate. This is particularly so in the response to acute ischaemia‐reperfusion injury (IRI). Following an acute episode of sustained myocardial ischaemia, the opening of the mitochondrial permeability transition pore (MPTP) in the first f...

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Detalles Bibliográficos
Autores principales: Ong, S‐B, Dongworth, R K, Cabrera‐Fuentes, H A, Hausenloy, D J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386982/
https://www.ncbi.nlm.nih.gov/pubmed/25393318
http://dx.doi.org/10.1111/bph.13013