Enhanced GABAergic synaptic transmission at VLPAG neurons and potent modulation by oxycodone in a bone cancer pain model

BACKGROUND AND PURPOSE: We demonstrated previously that oxycodone has potent antinociceptive effects at supraspinal sites. In this study, we investigated changes in neuronal function and antinociceptive mechanisms of oxycodone at ventrolateral periaqueductal gray (VLPAG) neurons, which are a major s...

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Detalles Bibliográficos
Autores principales: Takasu, Keiko, Ogawa, Koichi, Nakamura, Atsushi, Kanbara, Tomoe, Ono, Hiroko, Tomii, Takako, Morioka, Yasuhide, Hasegawa, Minoru, Shibasaki, Masahiro, Mori, Tomohisa, Suzuki, Tsutomu, Sakaguchi, Gaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386988/
https://www.ncbi.nlm.nih.gov/pubmed/25521524
http://dx.doi.org/10.1111/bph.13039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386988/
https://www.ncbi.nlm.nih.gov/pubmed/25521524
http://dx.doi.org/10.1111/bph.13039

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