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Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance

The identification of key tumorigenic events in Sonic Hedgehog subgroup medulloblastomas (MB(SHH)) will be essential for the development of individualized therapies and improved outcomes. However, beyond confirmation of characteristic SHH-pathway mutations, recent genome-wide sequencing studies have...

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Detalles Bibliográficos
Autores principales: Lindsey, Janet C., Kawauchi, Daisuke, Schwalbe, Ed C., Solecki, David J., Selby, Matthew P., McKinnon, Peter J., Olson, James M., Hayden, James T., Grundy, Richard G., Ellison, David W., Williamson, Daniel, Bailey, Simon, Roussel, Martine F., Clifford, Steven C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386991/
https://www.ncbi.nlm.nih.gov/pubmed/25531316
http://dx.doi.org/10.1038/onc.2014.405