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Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance
The identification of key tumorigenic events in Sonic Hedgehog subgroup medulloblastomas (MB(SHH)) will be essential for the development of individualized therapies and improved outcomes. However, beyond confirmation of characteristic SHH-pathway mutations, recent genome-wide sequencing studies have...
Autores principales: | Lindsey, Janet C., Kawauchi, Daisuke, Schwalbe, Ed C., Solecki, David J., Selby, Matthew P., McKinnon, Peter J., Olson, James M., Hayden, James T., Grundy, Richard G., Ellison, David W., Williamson, Daniel, Bailey, Simon, Roussel, Martine F., Clifford, Steven C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386991/ https://www.ncbi.nlm.nih.gov/pubmed/25531316 http://dx.doi.org/10.1038/onc.2014.405 |
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