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Differential roles of STAT3 in the initiation and growth of lung cancer

Signal transducer and activator of transcription 3 (STAT3) is linked to multiple cancers, including pulmonary adenocarcinoma. However, the role of STAT3 in lung cancer pathogenesis has not been determined. Using lung epithelial-specific inducible knockout strategies, we demonstrate that STAT3 plays...

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Detalles Bibliográficos
Autores principales: Zhou, Jingjiao, Qu, Zhaoxia, Yan, Shapei, Sun, Fan, Whitsett, Jeffrey A., Shapiro, Steven D., Xiao, Gutian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387125/
https://www.ncbi.nlm.nih.gov/pubmed/25284582
http://dx.doi.org/10.1038/onc.2014.318