Cargando…

Differential roles of STAT3 in the initiation and growth of lung cancer

Signal transducer and activator of transcription 3 (STAT3) is linked to multiple cancers, including pulmonary adenocarcinoma. However, the role of STAT3 in lung cancer pathogenesis has not been determined. Using lung epithelial-specific inducible knockout strategies, we demonstrate that STAT3 plays...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Jingjiao, Qu, Zhaoxia, Yan, Shapei, Sun, Fan, Whitsett, Jeffrey A., Shapiro, Steven D., Xiao, Gutian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387125/ https://www.ncbi.nlm.nih.gov/pubmed/25284582 http://dx.doi.org/10.1038/onc.2014.318

Ejemplares similares

Causative role of PDLIM2 epigenetic repression in lung cancer and therapeutic resistance
por: Sun, Fan, et al.
Publicado: (2019)

NF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function
por: Sun, Fan, et al.
Publicado: (2015)

PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease
por: Qu, Zhaoxia, et al.
Publicado: (2012)

Dual but not single PD-1 or TIM-3 blockade enhances oncolytic virotherapy in refractory lung cancer
por: Sun, Fan, et al.
Publicado: (2020)

PDLIM2 repression by ROS in alveolar macrophages promotes lung tumorigenesis
por: Li, Liwen, et al.
Publicado: (2021)

Human T-Cell Lymphotropic Virus: A Model of NF-κB-Associated Tumorigenesis
por: Qu, Zhaoxia, et al.
Publicado: (2011)

Identification and characterization of novel NF-kB dependent genes involved in HTLV-I pathogenesis
por: Qu, Zhaoxia, et al.
Publicado: (2015)

Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells
por: Xu, Yan, et al.
Publicado: (2007)

The critical role that STAT3 plays in glioma-initiating cells: STAT3 addiction in glioma
por: Ganguly, Debolina, et al.
Publicado: (2018)

The Akt1/IL-6/STAT3 pathway regulates growth of lung tumor initiating cells
por: Malanga, Donatella, et al.
Publicado: (2015)

Coordination of the canonical and noncanonical IKK/NF-κB signaling pathways in HTLV-I Tax-mediated tumorigenesis
por: Fu, Jing, et al.
Publicado: (2011)

NF-kappaB activation: Tax sumoylation is out, but what about Tax ubiquitination?
por: Xiao, Gutian
Publicado: (2012)

SLICE: determining cell differentiation and lineage based on single cell entropy
por: Guo, Minzhe, et al.
Publicado: (2017)

Inhibition of STAT3 signaling targets both tumor-initiating and differentiated cell populations in prostate cancer
por: Han, Zhiqiang, et al.
Publicado: (2014)

Kaposi's sarcoma herpesvirus (KSHV) microRNA K12-1 functions as an oncogene by activating NF-κB/IL-6/STAT3 signaling
por: Chen, Mingqing, et al.
Publicado: (2016)

Roles of N‐Myc and STAT interactor in cancer: From initiation to dissemination
por: Pruitt, Hawley C., et al.
Publicado: (2016)

Differential roles of STAT3 depending on the mechanism of STAT3 activation in gastric cancer cells
por: Okamoto, W, et al.
Publicado: (2011)

Comparative Effectiveness of Opioid Tapering or Abrupt Discontinuation vs No Dosage Change for Opioid Overdose or Suicide for Patients Receiving Stable Long-term Opioid Therapy
por: Larochelle, Marc R., et al.
Publicado: (2022)

SINCERA: A Pipeline for Single-Cell RNA-Seq Profiling Analysis
por: Guo, Minzhe, et al.
Publicado: (2015)

STAT3 but Not STAT1 Is Required for Astrocyte Differentiation
por: Hong, Seulgi, et al.
Publicado: (2014)

The Role of STAT3 in Non-Small Cell Lung Cancer
por: Harada, Daijiro, et al.
Publicado: (2014)

Regulation of Wnt/β-catenin signaling by posttranslational modifications
por: Gao, Chenxi, et al.
Publicado: (2014)

Maternal Synchronization of Gestational Length and Lung Maturation
por: Besnard, Valérie, et al.
Publicado: (2011)

RIP4 inhibits STAT3 signaling to sustain lung adenocarcinoma differentiation
por: Kopparam, Jawahar, et al.
Publicado: (2017)

Significance of Stat3 Signaling in Epithelial Cell Differentiation of Fetal Mouse Lungs
por: Kameyama, Hiroki, et al.
Publicado: (2017)

YAP regulates alveolar epithelial cell differentiation and AGER via NFIB/KLF5/NKX2-1
por: Gokey, Jason J., et al.
Publicado: (2021)

Sox17 Promotes Cell Cycle Progression and Inhibits TGF-β/Smad3 Signaling to Initiate Progenitor Cell Behavior in the Respiratory Epithelium
por: Lange, Alexander W., et al.
Publicado: (2009)

STAT3-Inducible Mouse ESCs: A Model to Study the Role of STAT3 in ESC Maintenance and Lineage Differentiation
por: Wong, Yu Qian, et al.
Publicado: (2018)

Reconstructing differentiation networks and their regulation from time series single-cell expression data
por: Ding, Jun, et al.
Publicado: (2018)

ERK, Akt, and STAT5 are Differentially Activated by the Two Growth Hormone Receptor Subtypes of a Teleost Fish (Oncorhynchus Mykiss)
por: Kittilson, Jeffrey D., et al.
Publicado: (2011)

Overexpressed HO-1 is associated with reduced STAT3 activation in preeclampsia placenta and inhibits STAT3 phosphorylation in placental JEG-3 cells under hypoxia
por: Qu, Hong-Mei, et al.
Publicado: (2016)

JAK1–STAT1–STAT3, a key pathway promoting proliferation and preventing premature differentiation of myoblasts
por: Sun, Luguo, et al.
Publicado: (2007)

Transcriptional Programs Controlling Perinatal Lung Maturation
por: Xu, Yan, et al.
Publicado: (2012)

Role of JAK/STAT in Interstitial Lung Diseases; Molecular and Cellular Mechanisms
por: Montero, Paula, et al.
Publicado: (2021)

Epithelial SCAP/INSIG/SREBP Signaling Regulates Multiple Biological Processes during Perinatal Lung Maturation
por: Bridges, James P., et al.
Publicado: (2014)

STAT3 roles in viral infection: antiviral or proviral?
por: Chang, Zhangmei, et al.
Publicado: (2018)

STAT3‐induced upregulation of lncRNA ABHD11‐AS1 promotes tumour progression in papillary thyroid carcinoma by regulating miR‐1301‐3p/STAT3 axis and PI3K/AKT signalling pathway
por: Wen, Juyi, et al.
Publicado: (2019)

The role of STAT3 and AhR in the differentiation of CD4(+) T cells into Th17 and Treg cells
por: Liu, Xingxing, et al.
Publicado: (2017)

STAT6 and lung inflammation
por: Walford, Hannah H, et al.
Publicado: (2013)

STAT4: An Initiator of Meta-Inflammation in Adipose Tissue?
por: Knudsen, Nelson H., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_t2vdm7tggrkm83qeqebmqe084s