Pharmacokinetic study of aldoxorubicin in patients with solid tumors

Introduction Aldoxorubicin, a prodrug of doxorubicin, binds covalently to serum albumin in the bloodstream and accumulates in tumors. Aldoxorubicin can be administered at doses several-fold higher than doxorubicin can, without associated acute cardiotoxicity. Purpose This study fully evaluated the p...

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Detalles Bibliográficos
Autores principales: Mita, Monica M., Natale, Ronald B., Wolin, Edward M., Laabs, Brenda, Dinh, Hillary, Wieland, Scott, Levitt, Daniel J., Mita, Alain C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Phase I Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387275/
https://www.ncbi.nlm.nih.gov/pubmed/25388939
http://dx.doi.org/10.1007/s10637-014-0183-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387275/
https://www.ncbi.nlm.nih.gov/pubmed/25388939
http://dx.doi.org/10.1007/s10637-014-0183-5

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