Inefficient clearance of myelin debris by microglia impairs remyelinating processes

An imbalance between remyelinating and demyelinating rates underlies degenerative processes in demyelinating diseases such as multiple sclerosis. An optimal therapeutic strategy would be to stimulate remyelination while limiting demyelination. Although accumulation of myelin debris impairs remyelina...

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Detalles Bibliográficos
Autores principales: Lampron, Antoine, Larochelle, Antoine, Laflamme, Nathalie, Préfontaine, Paul, Plante, Marie-Michèle, Sánchez, Maria Gabriela, Yong, V. Wee, Stys, Peter K., Tremblay, Marie-Ève, Rivest, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387282/
https://www.ncbi.nlm.nih.gov/pubmed/25779633
http://dx.doi.org/10.1084/jem.20141656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387282/
https://www.ncbi.nlm.nih.gov/pubmed/25779633
http://dx.doi.org/10.1084/jem.20141656

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