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Lin28b promotes fetal B lymphopoiesis through the transcription factor Arid3a

Mouse B cell precursors from fetal liver and adult bone marrow (BM) generate distinctive B cell progeny when transplanted into immunodeficient recipients, supporting a two-pathway model for B lymphopoiesis, fetal “B-1” and adult “B-2.” Recently, Lin28b was shown to be important for the switch betwee...

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Detalles Bibliográficos
Autores principales: Zhou, Yan, Li, Yue-Sheng, Bandi, Srinivasa Rao, Tang, Lingjuan, Shinton, Susan A., Hayakawa, Kyoko, Hardy, Richard R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387290/
https://www.ncbi.nlm.nih.gov/pubmed/25753579
http://dx.doi.org/10.1084/jem.20141510