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Heparanase activates the syndecan-syntenin-ALIX exosome pathway

Exosomes are secreted vesicles of endosomal origin involved in signaling processes. We recently showed that the syndecan heparan sulfate proteoglycans control the biogenesis of exosomes through their interaction with syntenin-1 and the endosomal-sorting complex required for transport accessory compo...

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Detalles Bibliográficos
Autores principales: Roucourt, Bart, Meeussen, Sofie, Bao, Jie, Zimmermann, Pascale, David, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387558/
https://www.ncbi.nlm.nih.gov/pubmed/25732677
http://dx.doi.org/10.1038/cr.2015.29