Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition

The sterol regulatory element-binding protein (SREBP) and SREBP cleavage-activating protein (SCAP) are central players in the SREBP pathway, which control the cellular lipid homeostasis. SCAP binds to SREBP through their carboxyl (C) domains and escorts SREBP from the endoplasmic reticulum to the Go...

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Detalles Bibliográficos
Autores principales: Gong, Xin, Li, Jingxian, Shao, Wei, Wu, Jianping, Qian, Hongwu, Ren, Ruobing, Espenshade, Peter, Yan, Nieng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387560/
https://www.ncbi.nlm.nih.gov/pubmed/25771684
http://dx.doi.org/10.1038/cr.2015.32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387560/
https://www.ncbi.nlm.nih.gov/pubmed/25771684
http://dx.doi.org/10.1038/cr.2015.32

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