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Bim and VDAC1 are hierarchically essential for mitochondrial ATF2 mediated cell death

BACKGROUND: ATF2 mediated cytochrome c release is the formation of a channel with some unknown factors larger than that of the individual proteins. BHS-only proteins (BH3s), such as Bim, could induce BAX and VDAC, forming a new channel. According to this facts, we can speculated that there is possib...

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Detalles Bibliográficos
Autores principales: Liu, Zhaoyun, Luo, Qianfu, Guo, Chunbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387661/
https://www.ncbi.nlm.nih.gov/pubmed/25852302
http://dx.doi.org/10.1186/s12935-015-0188-y