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Published sequences do not support transfer of oseltamivir resistance mutations from avian to human influenza A virus strains

BACKGROUND: Tamiflu (oseltamivir phosphate ester, OE) is a widely used antiviral active against influenza A virus. Its active metabolite, oseltamivir carboxylate (OC), is chemically stable and secreted into wastewater treatment plants. OC contamination of natural habitats of waterfowl might induce O...

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Detalles Bibliográficos
Autores principales: Norberg, Peter, Lindh, Magnus, Olofsson, Sigvard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387679/
https://www.ncbi.nlm.nih.gov/pubmed/25887656
http://dx.doi.org/10.1186/s12879-015-0860-9