Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span

Functional data indicate that specific histone modification enzymes can be key to longevity in Caenorhabditis elegans, but the molecular basis of how chromatin structure modulates longevity is not well understood. In this study, we profiled the genome-wide pattern of trimethylation of Lys36 on histo...

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Detalles Bibliográficos
Autores principales: Pu, Mintie, Ni, Zhuoyu, Wang, Minghui, Wang, Xiujuan, Wood, Jason G., Helfand, Stephen L., Yu, Haiyuan, Lee, Siu Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387714/
https://www.ncbi.nlm.nih.gov/pubmed/25838541
http://dx.doi.org/10.1101/gad.254144.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387714/
https://www.ncbi.nlm.nih.gov/pubmed/25838541
http://dx.doi.org/10.1101/gad.254144.114

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