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Conditional knockout of smooth muscle sodium calcium exchanger type‐1 lowers blood pressure and attenuates Angiotensin II‐salt hypertension

The functions of smooth muscle sodium calcium exchanger (NCX) in the vasculature are controversial and poorly understood. To determine the possible roles of NCX in the vascular phenotype and function, we developed a novel mouse model (SM‐NCX1 KO) in which the smooth muscle‐specific NCX type‐1 (NCX1)...

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Detalles Bibliográficos
Autores principales: Wang, Youhua, Chen, Ling, Li, Meng, Cha, Helen, Iwamoto, Takahiro, Zhang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387742/
https://www.ncbi.nlm.nih.gov/pubmed/25626872
http://dx.doi.org/10.14814/phy2.12273