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Expression of pigment epithelium‐derived factor and thrombospondin‐1 regulate proliferation and migration of retinal pigment epithelial cells

Age‐related macular degeneration (AMD) is the leading cause of vision loss among elderly. Although the pathogenesis of AMD is associated with retinal pigmented epithelium (RPE) dysfunction and abnormal neovascularization the detailed mechanisms remain unresolved. RPE is a specialized monolayer of ep...

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Detalles Bibliográficos
Autores principales: Farnoodian, Mitra, Kinter, James B., Yadranji Aghdam, Saeed, Zaitoun, Ismail, Sorenson, Christine M., Sheibani, Nader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387751/
https://www.ncbi.nlm.nih.gov/pubmed/25602019
http://dx.doi.org/10.14814/phy2.12266