Perlecan deficiency causes endothelial dysfunction by reducing the expression of endothelial nitric oxide synthase

Perlecan is a major heparan sulfate proteoglycan found in the subendothelial extracellular matrix of the vascular wall. The aim of this study was to investigate the role of perlecan in the regulation of vascular tone. A previously developed conditional perlecan‐deficient mouse model was used to meas...

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Detalles Bibliográficos
Autores principales: Nonaka, Risa, Iesaki, Takafumi, de Vega, Susana, Daida, Hiroyuki, Okada, Takao, Sasaki, Takako, Arikawa‐Hirasawa, Eri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387761/
https://www.ncbi.nlm.nih.gov/pubmed/25626871
http://dx.doi.org/10.14814/phy2.12272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387761/
https://www.ncbi.nlm.nih.gov/pubmed/25626871
http://dx.doi.org/10.14814/phy2.12272

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