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Tissue-specific and time-dependent regulation of the endothelin axis by the circadian clock protein Per1

AIMS: The present study is designed to consider a role for the circadian clock protein Per1 in the regulation of the endothelin axis in mouse kidney, lung, liver and heart. Renal endothelin-1 (ET-1) is a regulator of the epithelial sodium channel (ENaC) and blood pressure (BP), via activation of bot...

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Detalles Bibliográficos
Autores principales: Richards, Jacob, Welch, Amanda K., Barilovits, Sarah J., All, Sean, Cheng, Kit-Yan, Wingo, Charles S., Cain, Brian D., Gumz, Michelle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387882/
https://www.ncbi.nlm.nih.gov/pubmed/24721511
http://dx.doi.org/10.1016/j.lfs.2014.03.028