Development and Implementation of a Double-Blind Corticosteroid-Tapering Regimen for a Clinical Trial

We describe the design and operationalization of a blinded corticosteroid-tapering regimen for a randomized trial of tocilizumab in giant cell arteritis (GCA). To our knowledge, no clinical trial in any disease has ever employed a blinded corticosteroid-tapering regimen, but this was necessary to th...

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Detalles Bibliográficos
Autores principales: Collinson, Neil, Tuckwell, Katie, Habeck, Frank, Chapman, Monique, Klearman, Micki, Stone, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387940/
https://www.ncbi.nlm.nih.gov/pubmed/25878667
http://dx.doi.org/10.1155/2015/589841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387940/
https://www.ncbi.nlm.nih.gov/pubmed/25878667
http://dx.doi.org/10.1155/2015/589841

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