Differential Effects of IL-17A and TNF-α on Osteoblastic Differentiation of Isolated Synoviocytes and on Bone Explants from Arthritis Patients

OBJECTIVE: TNF-α and IL-17A act on fibroblast-like synoviocytes (FLS) and contribute to cytokine production, inflammation, and tissue destruction in rheumatoid arthritis (RA). The aim of this study was to compare their effects on osteogenic differentiation of isolated FLS and on whole bone explants...

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Detalles Bibliográficos
Autores principales: Osta, Bilal, Roux, Jean-Paul, Lavocat, Fabien, Pierre, Marlène, Ndongo-Thiam, Ndieme, Boivin, Georges, Miossec, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387961/
https://www.ncbi.nlm.nih.gov/pubmed/25904914
http://dx.doi.org/10.3389/fimmu.2015.00151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387961/
https://www.ncbi.nlm.nih.gov/pubmed/25904914
http://dx.doi.org/10.3389/fimmu.2015.00151

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