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Regulating Rac in the Nervous System: Molecular Function and Disease Implication of Rac GEFs and GAPs

Rho family GTPases, including RhoA, Rac1, and Cdc42 as the most studied members, are master regulators of actin cytoskeletal organization. Rho GTPases control various aspects of the nervous system and are associated with a number of neuropsychiatric and neurodegenerative diseases. The activity of Rh...

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Detalles Bibliográficos
Autores principales: Bai, Yanyang, Xiang, Xiaoliang, Liang, Chunmei, Shi, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388020/
https://www.ncbi.nlm.nih.gov/pubmed/25879033
http://dx.doi.org/10.1155/2015/632450