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Regulating Rac in the Nervous System: Molecular Function and Disease Implication of Rac GEFs and GAPs
Rho family GTPases, including RhoA, Rac1, and Cdc42 as the most studied members, are master regulators of actin cytoskeletal organization. Rho GTPases control various aspects of the nervous system and are associated with a number of neuropsychiatric and neurodegenerative diseases. The activity of Rh...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388020/ https://www.ncbi.nlm.nih.gov/pubmed/25879033 http://dx.doi.org/10.1155/2015/632450 |