A method for concentrating lipid peptide DNA and siRNA nanocomplexes that retains their structure and transfection efficiency

Nonviral gene and small interfering RNA (siRNA) delivery formulations are extensively used for biological and therapeutic research in cell culture experiments, but less so in in vivo and clinical research. Difficulties with formulating the nanoparticles for uniformity and stability at concentrations...

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Detalles Bibliográficos
Autores principales: Tagalakis, Aristides D, Castellaro, Sara, Zhou, Haiyan, Bienemann, Alison, Munye, Mustafa M, McCarthy, David, White, Edward A, Hart, Stephen L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388080/
https://www.ncbi.nlm.nih.gov/pubmed/25878500
http://dx.doi.org/10.2147/IJN.S78935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388080/
https://www.ncbi.nlm.nih.gov/pubmed/25878500
http://dx.doi.org/10.2147/IJN.S78935

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