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A method for concentrating lipid peptide DNA and siRNA nanocomplexes that retains their structure and transfection efficiency
Nonviral gene and small interfering RNA (siRNA) delivery formulations are extensively used for biological and therapeutic research in cell culture experiments, but less so in in vivo and clinical research. Difficulties with formulating the nanoparticles for uniformity and stability at concentrations...
Autores principales: | Tagalakis, Aristides D, Castellaro, Sara, Zhou, Haiyan, Bienemann, Alison, Munye, Mustafa M, McCarthy, David, White, Edward A, Hart, Stephen L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388080/ https://www.ncbi.nlm.nih.gov/pubmed/25878500 http://dx.doi.org/10.2147/IJN.S78935 |
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