Combination of X-ray crystallography, SAXS and DEER to obtain the structure of the FnIII-3,4 domains of integrin α6β4

Integrin α6β4 is a major component of hemidesmosomes that mediate the stable anchorage of epithelial cells to the underlying basement membrane. Integrin α6β4 has also been implicated in cell proliferation and migration and in carcinoma progression. The third and fourth fibronectin type III domains (...

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Detalles Bibliográficos
Autores principales: Alonso-García, Noelia, García-Rubio, Inés, Manso, José A., Buey, Rubén M., Urien, Hector, Sonnenberg, Arnoud, Jeschke, Gunnar, de Pereda, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388270/
https://www.ncbi.nlm.nih.gov/pubmed/25849406
http://dx.doi.org/10.1107/S1399004715002485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388270/
https://www.ncbi.nlm.nih.gov/pubmed/25849406
http://dx.doi.org/10.1107/S1399004715002485

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