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A Stable Chimeric Fibroblast Growth Factor (FGF) Can Successfully Replace Basic FGF in Human Pluripotent Stem Cell Culture

Fibroblast growth factors (FGFs) are essential for maintaining self-renewal in human embryonic stem cells and induced pluripotent stem cells. Recombinant basic FGF (bFGF or FGF2) is conventionally used to culture pluripotent stem cells; however, because of the instability of bFGF, repeated addition...

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Detalles Bibliográficos
Autores principales: Onuma, Yasuko, Higuchi, Kumiko, Aiki, Yasuhiko, Shu, Yujing, Asada, Masahiro, Asashima, Makoto, Suzuki, Masashi, Imamura, Toru, Ito, Yuzuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388338/
https://www.ncbi.nlm.nih.gov/pubmed/25850016
http://dx.doi.org/10.1371/journal.pone.0118931