Nucleosides Present on Phlebotomine Saliva Induce Immunossuppression and Promote the Infection Establishment

BACKGROUND: Sand fly saliva plays a crucial role in establishing Leishmania infection. We identified adenosine (ADO) and adenosine monophosphate (AMP) as active pharmacologic compounds present in Phlebotomus papatasi saliva that inhibit dendritic cell (DC) functions through a PGE(2)/IL 10-dependent...

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Detalles Bibliográficos
Autores principales: Carregaro, Vanessa, Ribeiro, José M., Valenzuela, Jesus G., Souza-Júnior, Djalma L., Costa, Diego L., Oliveira, Carlo J. F., Sacramento, Laís A., Nascimento, Manuela S. L., Milanezi, Cristiane M., Cunha, Fernando Q., Silva, João S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388340/
https://www.ncbi.nlm.nih.gov/pubmed/25849562
http://dx.doi.org/10.1371/journal.pntd.0003600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388340/
https://www.ncbi.nlm.nih.gov/pubmed/25849562
http://dx.doi.org/10.1371/journal.pntd.0003600

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