Suppressor of Cytokine Signaling (SOCS) Genes Are Silenced by DNA Hypermethylation and Histone Deacetylation and Regulate Response to Radiotherapy in Cervical Cancer Cells

Suppressor of cytokine signaling (SOCS) family is an important negative regulator of cytokine signaling and deregulation of SOCS has been involved in many types of cancer. All cervical cancer cell lines tested showed lower expression of SOCS1, SOCS3, and SOCS5 than normal tissue or cell lines. The i...

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Detalles Bibliográficos
Autores principales: Kim, Moon-Hong, Kim, Moon-Sun, Kim, Wonwoo, Kang, Mi Ae, Cacalano, Nicholas A., Kang, Soon-Beom, Shin, Young-Joo, Jeong, Jae-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388447/
https://www.ncbi.nlm.nih.gov/pubmed/25849377
http://dx.doi.org/10.1371/journal.pone.0123133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388447/
https://www.ncbi.nlm.nih.gov/pubmed/25849377
http://dx.doi.org/10.1371/journal.pone.0123133

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