Leukocyte-Derived IFN-α/β and Epithelial IFN-λ Constitute a Compartmentalized Mucosal Defense System that Restricts Enteric Virus Infections

Epithelial cells are a major port of entry for many viruses, but the molecular networks which protect barrier surfaces against viral infections are incompletely understood. Viral infections induce simultaneous production of type I (IFN-α/β) and type III (IFN-λ) interferons. All nucleated cells are b...

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Detalles Bibliográficos
Autores principales: Mahlakõiv, Tanel, Hernandez, Pedro, Gronke, Konrad, Diefenbach, Andreas, Staeheli, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388470/
https://www.ncbi.nlm.nih.gov/pubmed/25849543
http://dx.doi.org/10.1371/journal.ppat.1004782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388470/
https://www.ncbi.nlm.nih.gov/pubmed/25849543
http://dx.doi.org/10.1371/journal.ppat.1004782

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