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Engagement of Fas on Macrophages Modulates Poly I:C Induced Cytokine Production with Specific Enhancement of IP-10

Viral double-stranded RNA (dsRNA) is recognised by pathogen recognition receptors such as Toll-Like Receptor 3 (TLR3) and retinoic acid inducible gene-I (RIG-I), and results in cytokine and interferon production. Fas, a well characterised death receptor, has recently been shown to play a role in the...

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Detalles Bibliográficos
Autores principales: Lyons, Caitriona, Fernandes, Philana, Fanning, Liam J., Houston, Aileen, Brint, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388479/
https://www.ncbi.nlm.nih.gov/pubmed/25849666
http://dx.doi.org/10.1371/journal.pone.0123635