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Quantitative Profiling of Brain Lipid Raft Proteome in a Mouse Model of Fragile X Syndrome

Fragile X Syndrome, a leading cause of inherited intellectual disability and autism, arises from transcriptional silencing of the FMR1 gene encoding an RNA-binding protein, Fragile X Mental Retardation Protein (FMRP). FMRP can regulate the expression of approximately 4% of brain transcripts through...

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Detalles Bibliográficos
Autores principales: Kalinowska, Magdalena, Castillo, Catherine, Francesconi, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388542/
https://www.ncbi.nlm.nih.gov/pubmed/25849048
http://dx.doi.org/10.1371/journal.pone.0121464