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Macrocyclic Lactones Differ in Interaction with Recombinant P-Glycoprotein 9 of the Parasitic Nematode Cylicocylus elongatus and Ketoconazole in a Yeast Growth Assay

Macrocyclic lactones (MLs) are widely used parasiticides against nematodes and arthropods, but resistance is frequently observed in parasitic nematodes of horses and livestock. Reports claiming resistance or decreased susceptibility in human nematodes are increasing. Since no target site directed ML...

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Detalles Bibliográficos
Autores principales: Kaschny, Maximiliane, Demeler, Janina, Janssen, I. Jana I., Kuzmina, Tetiana A., Besognet, Bruno, Kanellos, Theo, Kerboeuf, Dominique, von Samson-Himmelstjerna, Georg, Krücken, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388562/
https://www.ncbi.nlm.nih.gov/pubmed/25849454
http://dx.doi.org/10.1371/journal.ppat.1004781