The Spectrin cytoskeleton regulates the Hippo signalling pathway

The Spectrin cytoskeleton is known to be polarised in epithelial cells, yet its role remains poorly understood. Here, we show that the Spectrin cytoskeleton controls Hippo signalling. In the developing Drosophila wing and eye, loss of apical Spectrins (alpha/beta-heavy dimers) produces tissue overgr...

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Detalles Bibliográficos
Autores principales: Fletcher, Georgina C, Elbediwy, Ahmed, Khanal, Ichha, Ribeiro, Paulo S, Tapon, Nic, Thompson, Barry J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388601/
https://www.ncbi.nlm.nih.gov/pubmed/25712476
http://dx.doi.org/10.15252/embj.201489642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388601/
https://www.ncbi.nlm.nih.gov/pubmed/25712476
http://dx.doi.org/10.15252/embj.201489642

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