The cAMP phosphodiesterase Prune localizes to the mitochondrial matrix and promotes mtDNA replication by stabilizing TFAM

Compartmentalized cAMP signaling regulates mitochondrial dynamics, morphology, and oxidative phosphorylation. However, regulators of the mitochondrial cAMP pathway, and its broad impact on organelle function, remain to be explored. Here, we report that Drosophila Prune is a cyclic nucleotide phospho...

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Detalles Bibliográficos
Autores principales: Zhang, Fan, Qi, Yun, Zhou, Kiet, Zhang, Guofeng, Linask, Kaari, Xu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Scientific Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388618/
https://www.ncbi.nlm.nih.gov/pubmed/25648146
http://dx.doi.org/10.15252/embr.201439636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388618/
https://www.ncbi.nlm.nih.gov/pubmed/25648146
http://dx.doi.org/10.15252/embr.201439636

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