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Uniform Sampling of Steady States in Metabolic Networks: Heterogeneous Scales and Rounding

The uniform sampling of convex polytopes is an interesting computational problem with many applications in inference from linear constraints, but the performances of sampling algorithms can be affected by ill-conditioning. This is the case of inferring the feasible steady states in models of metabol...

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Detalles Bibliográficos
Autores principales: De Martino, Daniele, Mori, Matteo, Parisi, Valerio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388631/
https://www.ncbi.nlm.nih.gov/pubmed/25849140
http://dx.doi.org/10.1371/journal.pone.0122670